Log

[2026-04-10] translate | Prusiner (1982)

  • Translated wiki/sources/prusiner-1982-novel-proteinaceous-infectious-particles.md -> wiki-tr/sources/prusiner-1982-novel-proteinaceous-infectious-particles.md
  • Translated wiki/mechanisms/prion-hypothesis.md -> wiki-tr/mechanisms/prion-hypothesis.md
  • Translated wiki/mechanisms/protein-only-inheritance.md -> wiki-tr/mechanisms/protein-only-inheritance.md
  • Translated wiki/conditions/cjd.md -> wiki-tr/conditions/cjd.md
  • Updated index-tr.md
  • (Manual translation performed due to environment limitations)

[2026-04-10] ingest | Prusiner (1982) — Novel Proteinaceous Infectious Particles Cause Scrapie

  • Source: raw/prusiner.pdf
  • Created source: wiki/sources/prusiner-1982-novel-proteinaceous-infectious-particles.md
  • Created condition: cjd.md
  • Created mechanisms: prion-hypothesis.md · protein-only-inheritance.md
  • Updated: index.md

[2026-04-10] translate | Hardy & Higgins (1992)

  • Translated wiki/sources/hardy-higgins-1992-amyloid-cascade-hypothesis.md -> wiki-tr/sources/hardy-higgins-1992-amyloid-cascade-hypothesis.md
  • Translated wiki/mechanisms/amyloid-cascade-hypothesis.md -> wiki-tr/mechanisms/amyloid-cascade-hypothesis.md
  • Translated wiki/mechanisms/tau-tangles.md -> wiki-tr/mechanisms/tau-tangles.md
  • Translated wiki/mechanisms/calcium-homeostasis-dysregulation.md -> wiki-tr/mechanisms/calcium-homeostasis-dysregulation.md
  • Updated wiki-tr/conditions/alzheimers-disease.md
  • Updated index-tr.md
  • (Manual translation performed due to environment limitations)

[2026-04-10] ingest | Hardy & Higgins (1992) — Alzheimer’s Disease: The Amyloid Cascade Hypothesis

  • Source: raw/The Amyloid .pdf
  • Created source: wiki/sources/hardy-higgins-1992-amyloid-cascade-hypothesis.md
  • Created mechanisms: amyloid-cascade-hypothesis.md · tau-tangles.md · calcium-homeostasis-dysregulation.md
  • Updated condition: alzheimers-disease.md
  • Updated: index.md

[2026-04-08] translate | Crary (2024)

  • Translated wiki/sources/crary-2024-neurodegeneration-update.md -> wiki-tr/sources/crary-2024-neurodegeneration-update.md
  • Translated wiki/conditions/alzheimers-disease.md -> wiki-tr/conditions/alzheimers-disease.md
  • Translated wiki/conditions/cte.md -> wiki-tr/conditions/cte.md
  • Translated wiki/mechanisms/viral-links-ndd.md -> wiki-tr/mechanisms/viral-links-ndd.md
  • Updated wiki-tr/mechanisms/epigenetic-regulation.md
  • Updated index-tr.md
  • (Manual translation performed)

[2026-04-08] ingest | Crary (2024) — Neurodegeneration: 2024 update

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  • Source: raw/neuroden-update2024.pdf
  • Created: wiki/sources/crary-2024-neurodegeneration-update.md
  • Created conditions: alzheimers-disease.md · cte.md
  • Created mechanism: viral-links-ndd.md
  • Updated mechanism: epigenetic-regulation.md (added Histological Brain Age)
  • Updated: index.md

[2026-04-08] translate | McCutcheon et al. (2020)

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  • Translated wiki/sources/mccutcheon-2020-dopamine-glutamate-schizophrenia.md -> wiki-tr/sources/mccutcheon-2020-dopamine-glutamate-schizophrenia.md
  • Translated wiki/mechanisms/glutamate-hypothesis.md -> wiki-tr/mechanisms/glutamate-hypothesis.md
  • Updated wiki-tr/conditions/schizophrenia.md
  • Updated index-tr.md
  • (Manual translation performed)

[2026-04-08] ingest | McCutcheon et al. (2020) — Dopamine and glutamate in schizophrenia

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  • Source: raw/dopa-schiz.pdf
  • Created: wiki/sources/mccutcheon-2020-dopamine-glutamate-schizophrenia.md
  • Created mechanism: glutamate-hypothesis.md
  • Updated condition: schizophrenia.md (added glutamate-dopamine interaction)
  • Updated: index.md

[2026-04-08] translate | Howes & Murray (2014)

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  • Translated index.md -> index-tr.md
  • Translated wiki/sources/howes-murray-2014-schizophrenia-integrated-model.md -> wiki-tr/sources/howes-murray-2014-schizophrenia-integrated-model.md
  • Translated wiki/mechanisms/aberrant-salience.md -> wiki-tr/mechanisms/aberrant-salience.md
  • Updated wiki-tr/conditions/schizophrenia.md
  • Updated wiki-tr/mechanisms/dopamine-reward-system.md
  • (Manual translation performed due to script environment limitations)

[2026-04-08] ingest | Howes & Murray (2014) — Schizophrenia: an integrated

…

There is change on user

  • Source: raw/schizo-murray.pdf
  • Created: wiki/sources/howes-murray-2014-schizophrenia-integrated-model.md
  • Created mechanism: aberrant-salience.md
  • Updated condition: schizophrenia.md (added integrated model and presynaptic shift)
  • Updated mechanism: dopamine-reward-system.md (added presynaptic shift in SCZ and added new systems for Alzheimer)
  • Updated: index.md

[2026-04-07] ingest | Koob & Volkow (2016) — Neurobiology of Addiction: A Neurocircuitry Analysis

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  • Source: raw/neurobiology of addiction.pdf
  • Created: wiki/sources/koob-volkow-2016-neurobiology-addiction.md
  • Created conditions: addiction.md
  • Created mechanisms: dopamine-reward-system.md · anti-reward-stress-systems.md · executive-function-dysregulation.md
  • Created debates: addiction-as-brain-disease.md
  • Updated: wiki/mechanisms/epigenetic-regulation.md (added Addiction link and Koob source)
  • Updated: wiki/conditions/depression.md (added Anti-Reward and Stress Systems link)
  • Updated: index.md (all new pages added)